The Gluten Controversy

breadI love bread. I absolutely love it! Slather it with butter or dip it into extra virgin olive oil, and I’m in seventh heaven. So I was relieved years ago when a food allergy test came up negative for gluten sensitivity. That being said, I’ve read books by a number of folks who recommend jumping on the “gluten free” bandwagon, especially if you’ve received any form of autoimmune diagnosis.

A gluten-free diet is a no-brainer for folks with celiac disease (~1% of the population). Gluten wreaks havoc on their intestines and impairs their ability to absorb nutrients from foods. An even smaller percentage of the population tests positive for a food allergy to wheat and should avoid eating it. Moreover, wheat-related antibodies may cross-react with dairy proteins, oats, brewer’s yeast, baker’s yeast, sorghum, millet, corn, rice, and potatoes, causing an allergic response to these foods as well. Other folks claim to be “gluten sensitive” – i.e., they report feeling better when avoiding gluten even though blood tests do not suggest an autoimmune or allergic response.

Common symptoms of food allergies and sensitivities include bloating, abdominal pain, bowel habit abnormalities, headaches, fatigue, depression, joint and muscle pain, numbness in one’s extremities, dermatitis, and anemia. These symptoms are also associated with small intestine bacteria overgrowth, fructose intolerance, lactose intolerance, microscopic colitis, and other causes. By eliminating the offending foods (including junk food) and increasing consumption of fruits, vegetables, whole grains, and lean proteins for an extended period of time, the body’s adverse response can be avoided.

The prevelence of gluten-related disease, allergy, and sensitivity may seem odd given that wheat, barley, and rye have been staples in the human diet for centuries. Why are we having so much trouble with them now?

According to autoimmune disease pundits, today’s breads have far more gluten than the ones our ancestors ate. This deluge of gluten comes with an excess of prolamins (a type of lectin) and protease inhibitors that challenge our standard complement of digestive enzymes. So when we eat modern day wheat-, barley-, and rye-based products, our bodies can’t break the complex proteins apart into essential amino acids from which they synthesize fuel. And when undigested food hangs around the gut, it feeds unhealthy pathogens which deprive our life-sustaining bacteria of vital nutrients. Gluten also has the ability to permeate the gut wall in between and through the cell lining. In fact, intracellular transport of prolamins has been associated with a dying back of cells in the lining, leaving a hole. Leaks and holes allow partially digested foods and pathogens to enter the bloodstream, giving rise to an immune response.

In Wheat Belly, Cardiologist William Davis, MD makes the connection between wheat consumption and the rise of obesity in the United States. He claims that processed wheat has a high glycemic index with elevates blood sugar, stimulates appetite, and generates withdrawal symptoms upon its removal. It is associated with a rise in visceral fat accumulation (a.k.a., belly fat) which engenders a host of inflammatory responses. Its production of Advanced Glycation End (AGE) products also accelerates aging.

Finally, famed neurologist Dr. David Perlmutter tells us that gluten sensitivity damages neural networks. Since the brain lacks pain receptors, gluten-induced cognitive impairment might be taking hold without an obvious physical trigger to alert the affected individual of a problem.

Having taken in all this information, I decided to visit, a non-commercial, science-based public service provided by Dr. Michael Greger, MD that offers the latest in nutrition research via bite-sized videos. His gluten-oriented videos offer a different perspective:

  • A small percent of the population has celiac disease, a wheat allergy, or gluten sensitivity. For the ~98% of us who fall outside that circle, gluten is perfectly safe to consume.
  • Whole grains are health promoting. They’ve been linked to reduced risk of coronary artery disease, cancer, diabetes, obesity, and other chronic diseases.
  • According to Dr. Yolanda Saz of IATA, a gluten-free diet may adversely affect gut health and immune function for those who do not have celiac disease or non-celiac gluten sensitivity. In fact, a study by Drs. Horiguchi, Horiguchi, and Suzuki showed that gluten consumption is associated with a significant increase in NK cell activity, which improves the body’s ability to fight tumor development and viral infections.
  • High gluten bread showed a greater positive impact on triglycerides than regular bread.
  • A self-prescribed gluten-free diet impedes the detection of bona fide celiac disease. When this disease is present, even a seemingly miniscule amount of gluten can have a severe impact. When sufferers do not know they have it, they could be taking in these miniscule helpings through an unintentional lack of vigilance.

As I said, I love bread, so it’s far from easy for me to give it up. I haven’t had a bite for 10 weeks and 4 days (but who’s counting?) Still, I haven’t closed the door on gluten. I’ll likely explore options for adding whole grains into my diet while leaving the processed stuff out.



Go to and then type “gluten” in the search box!

The Paleo Approach: Reverse Autoimmune Disease and Heal Your Body, by Sarah Ballantyne, ©2016

Wheat Belly: Lose the Wheat, Lose the Weight, and Find Your Path Back to Health, by William Davis, MD, ©2011

The Autoimmune Fix: How to Stop the Hidden Autoimmune Damage That Keeps You Sick, Fat, and Tired Before It Turns Into Disease, by Tom O’Bryan, MD, ©2016

Grain Brain: The Surprising Truth About Wheat, Corn, and Sugar – Your Brain’s Silent Killers, by David Perlmutter, MD, ©2013